Back to search

Peptide record

TPDB09201

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09201
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KGRGKQGGKVRAKAKTRSS
Physicochemical Analysis
C82H154N34O24
NDCEHILMFPWY
K
2000.34
12.72
8
0
3
+8
8.13
-1.716
25.79
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
1
Q
4
G
0
H
0
I
0
L
5
K
0
M
0
F
0
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C82H154N34O24
2000.34
12.72
+8
8.13
-1.716
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5-15 µg/mL

Target

L. garvieae

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
gainst fish-specific pathogens A. salmonicida, C. aquatilis, Y. ruckeri, E. ictaluri, and L. garvieae (MIC 5-15 ug/ml).
Evidence 2 Activity

Activity

MIC
Antifungal
5-15 µg/mL

Target

L. garvieae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
gainst fish-specific pathogens A. salmonicida, C. aquatilis, Y. ruckeri, E. ictaluri, and L. garvieae (MIC 5-15 ug/ml).
Evidence 3 Activity

Activity

MIC
Antiparasitic
5-15 µg/mL

Target

L. garvieae

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
gainst fish-specific pathogens A. salmonicida, C. aquatilis, Y. ruckeri, E. ictaluri, and L. garvieae (MIC 5-15 ug/ml).
Evidence 4 Activity

Activity

MIC
Antiviral
5-15 µg/mL

Target

L. garvieae

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
gainst fish-specific pathogens A. salmonicida, C. aquatilis, Y. ruckeri, E. ictaluri, and L. garvieae (MIC 5-15 ug/ml).
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. | FEBS Lett | 1998
Evidence 6 Activity

Activity

50% Cell death
Toxicity
>50.0 µM
Cytotoxic
50% Cell death | >50.0 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010