TPDB

3D PDB MODEL

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TPDB ID TPDB09198

Activity

Antibacterial Anticancer Antifungal Toxicity

Activity_category_statistics

Anti-infective peptides Cancer-related peptides Toxicity and safety peptides

Database_Source

AntiBP3 Peptipedia dbACP Antifungipept CAFPdb dbAMP ToxinPred 3.0

Sequence_Type

standard

Has_Modification No

Description A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, dbACP, and other sources, with an available 3D structural model.

Sequence

FLSLIPKIAGGIASLVKDL

FASTA

>TPDB09198|Antibacterial;Anticancer;Antifungal;Toxicity|length=19
FLSLIPKIAGGIASLVKDL

Formula C93H159N21O24

Absent Amino Acids RNCEQHMTWY

Common Amino Acids L

Mass 1955.41

PI 9.88

Basic Residues 2

Acidic Residues 1

Hydrophobic Residues 11

Net Charge +1

Boman Index -0.63

Hydrophobicity 1.263

Aliphatic Index 169.47

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 2

number

2

A

0

R

0

N

1

D

0

C

0

E

0

Q

2

G

0

H

3

I

4

L

2

K

0

M

1

F

1

P

2

S

0

T

0

W

0

Y

1

V

Amino Acid Distribution

A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 4 K: 2 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1

Length

19

Formula

C93H159N21O24

Mass

1955.41

PI

9.88

Net Charge

+1

Boman Index

-0.63

Hydrophobicity

1.263

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.

Evidence Text

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 100 uM), and C. albicans (MIC 100 uM). Updated 7/2018 7/2021.

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP

Other

Evidence Text

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 100 uM), and C. albicans (MIC 100 uM). Updated 7/2018 7/2021.

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µM

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP

Other

Evidence Text

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 100 uM), and C. albicans (MIC 100 uM). Updated 7/2018 7/2021.

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.

Evidence Text

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 100 uM), and C. albicans (MIC 100 uM). Updated 7/2018 7/2021.

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 100 uM), and C. albicans (MIC 100 uM). Updated 7/2018 7/2021.

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µM

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Evidence Text

Active against E. coli (MIC 100 uM), S. epidermidis (MIC 100 uM), and C. albicans (MIC 100 uM). Updated 7/2018 7/2021.