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Peptide record

TPDB09193

Antibacterial Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09193
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RLGTALPALLKTLLAGLNG
Physicochemical Analysis
C86H154N24O23
DCEQHIMFSWYV
L
1892.32
11.49
2
0
10
+2
-1.45
0.837
159.47
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
3
Residue Composition
number
3
A
1
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
7
L
1
K
0
M
0
F
1
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 7 K: 1 M: 0 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C86H154N24O23
1892.32
11.49
+2
-1.45
0.837
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
17 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against S. aureus (MIC 17 uM) and E. coli (MIC 17 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
17 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against S. aureus (MIC 17 uM) and E. coli (MIC 17 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
17 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 17 uM) and E. coli (MIC 17 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
17 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active against S. aureus (MIC 17 uM) and E. coli (MIC 17 uM).
Evidence 5 Activity

Activity

100% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
100% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides from skin secretions of Hypsiboas pulchellus (Anura: Hylidae). | J Nat Prod | 2014
Evidence 6 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.