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Peptide record

TPDB09189

Antibacterial Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09189
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KIFGAIWPLALGALKNLIK
Physicochemical Analysis
C102H168N24O21
RDCEQHMSTYV
L
2066.60
10.84
3
0
12
+3
-2.80
0.968
159.47
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
266.14
1
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
4
L
3
K
0
M
1
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 4 K: 3 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
19
C102H168N24O21
2066.60
10.84
+3
-2.80
0.968
Evidence Records 3 records
Evidence 1 Activity

Activity

14% Hemolysis
Toxicity
25000 µM
Hemolytic Cytotoxic
14% Hemolysis | 25000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evaluation of cytotoxicity features of antimicrobial peptides with potential to control bacterial diseases of citrus. | PLoS One | 2018
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
4 µM
Hemolytic Cytotoxic
50% Hemolysis | 4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of N-terminus modifications on the biological activity, membrane interaction, and secondary structure of the antimicrobial peptide hylin-a1. | Biopolymers | 2011
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis