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Peptide record

TPDB09188

Antibacterial Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09188
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ISQSDAILSAIWSGIKSLF
Physicochemical Analysis
C94H150N22O28
RNCEHMPTYV
S
2036.36
6.75
1
1
10
-0
-2.22
0.832
133.68
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
270.09
6
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
1
Q
1
G
0
H
4
I
2
L
1
K
0
M
1
F
0
P
5
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 4 L: 2 K: 1 M: 0 F: 1 P: 0 S: 5 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
19
C94H150N22O28
2036.36
6.75
-0
-2.22
0.832
Evidence Records 5 records
Evidence 1 Activity

Activity

EC50
Toxicity
15.71 µM
Cytotoxic
EC50 | 15.71 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
2.36 µM
Hemolytic Cytotoxic
10% Hemolysis | 2.36 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
129 µM
Hemolytic Cytotoxic
50% Hemolysis | 129 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 4 Activity

Activity

90% Hemolysis
Toxicity
7033.22 µM
Hemolytic Cytotoxic
90% Hemolysis | 7033.22 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Bioactivity of Natural and Engineered Antimicrobial Peptides from Venom of the Scorpions Urodacus yaschenkoi and U. manicatus. | Toxins (Basel) | 2017
Evidence 5 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.