Back to search

Peptide record

TPDB09181

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09181
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
GSKKPVPIIYCNRRKCQRM
Physicochemical Analysis
C97H169N33O24S3
ADEHLFTW
RK
2277.80
10.88
6
0
5
+6
5.24
-0.937
56.32
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
70.90
6
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
1
Q
1
G
0
H
2
I
0
L
3
K
1
M
0
F
2
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 0 K: 3 M: 1 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
19
C97H169N33O24S3
2277.80
10.88
+6
5.24
-0.937
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.6 µM

Target

Escherichia coli HB 101

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli HB 101 (MIC 2.6 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 10.4 uM), B. subtilis (MIC 5.2 uM), and
Evidence 2 Activity

Activity

MIC
Antibacterial
1.3 µM

Target

S. typhimurium

Source & Reference

dbAMP

Other

active against E. coli HB 101 (MIC 2.6 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 10.4 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
10.4 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

active against E. coli HB 101 (MIC 2.6 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 10.4 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
5.2 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

st E. coli HB 101 (MIC 2.6 uM), S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 10.4 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
10.4 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

, S. typhimurium (MIC 1.3 uM), P. aeruginosa (MIC 10.4 uM), B. subtilis (MIC 5.2 uM), and S. aureus (MIC 10.4 uM).
Evidence 6 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Role of amino acid residues within the disulfide loop of thanatin, a potent antibiotic peptide. | J Biochem Mol Biol | 2002