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Peptide record

TPDB09167

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09167
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
RRWCFRVCYRGRFCYRKCR
Physicochemical Analysis
C114H176N42O22S4
ANDEQHILMPST
R
2615.16
11.15
8
0
6
+8
-0.21
-1.026
15.26
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8730
333.82
6
Residue Composition
number
0
A
7
R
0
N
0
D
4
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
2
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
19
C114H176N42O22S4
2615.16
11.15
+8
-0.21
-1.026
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
42.6 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 42.6 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers. | Biochemistry | 2000
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis