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Peptide record

TPDB09161

Antibacterial Antifungal standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09161
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
APKAMRLLRRLLRLQKKGI
Physicochemical Analysis
C101H189N35O21S1
NDCEHFSTWYV
L
2261.89
12.88
7
0
9
+7
3.57
-0.326
133.68
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
5
L
3
K
1
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 5 K: 3 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C101H189N35O21S1
2261.89
12.88
+7
3.57
-0.326
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml),
Evidence 2 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

P. putida

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml),
Evidence 3 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi
Evidence 4 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S
Evidence 5 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

, P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/
Evidence 6 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

S. mutans

Source & Reference

dbAMP

Other

, S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC
Evidence 7 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

C. neoformans

Source & Reference

dbAMP

Other

Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC 0.5 ug/ml).
Evidence 8 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP

Other

), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC 0.5 ug/ml).
Evidence 9 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

ns (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC 0.5 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml),
Evidence 11 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

P. putida

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml),
Evidence 12 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi
Evidence 13 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Gram- E. coli (MIC 1 ug/ml), P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S
Evidence 14 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, P. putida (MIC 1 ug/ml), S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/
Evidence 15 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

S. mutans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

, S. enteritidis (MIC 1 ug/ml), Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC
Evidence 16 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

C. neoformans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Gram+ B. subtilis (MIC 1 ug/ml), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC 0.5 ug/ml).
Evidence 17 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), S. aureus (MIC 2 ug/ml), S. mutans (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC 0.5 ug/ml).
Evidence 18 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ns (MIC 1 ug/ml), fungi C. neoformans (MIC 0.5 ug/ml), S. cerevisiae (MIC 0.5 ug/ml), and C. albicans (MIC 0.5 ug/ml).