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Peptide record

TPDB09158

Antibacterial Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09158
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
WKKVFKRLEKLFSKIWNWK
Physicochemical Analysis
C128H194N32O24
ADCQGHMPTY
K
2565.15
11.19
7
1
9
+6
0.15
-0.868
76.84
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
643.24
2
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
2
L
6
K
0
M
2
F
0
P
1
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 6 M: 0 F: 2 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
19
C128H194N32O24
2565.15
11.19
+6
0.15
-0.868
Evidence Records 2 records
Evidence 1 Activity

Activity

95% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
95% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions. | Biochim Biophys Acta | 2008
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis