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Peptide record

TPDB09154

Antibacterial Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09154
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KWARLWRWFRITRWLWYIK
Physicochemical Analysis
C140H198N38O22
NDCEQGHMPSV
W
2765.35
12.41
6
0
12
+6
-7.87
-0.584
87.37
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
28990
1048.33
2
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
2
K
0
M
1
F
0
P
0
S
1
T
5
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 2 M: 0 F: 1 P: 0 S: 0 T: 1 W: 5 Y: 1 V: 0
Chemical Descriptors
19
C140H198N38O22
2765.35
12.41
+6
-7.87
-0.584
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
7-14 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 7-14 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of a novel tryptophan-rich membrane-active antimicrobial peptide from the membrane-proximal region of the HIV glycoprotein, gp41. | Beilstein J Org Chem | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis