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Peptide record

TPDB09153

Antibacterial Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09153
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KWAKKWKWFAKAAWKWYKK
Physicochemical Analysis
C133H186N32O21
RNDCEQGHILMPSTV
K
2569.14
11.02
8
0
11
+8
-4.08
-1.421
21.05
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
28990
1128.39
1
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
8
K
0
M
1
F
0
P
0
S
0
T
5
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 8 M: 0 F: 1 P: 0 S: 0 T: 0 W: 5 Y: 1 V: 0
Chemical Descriptors
19
C133H186N32O21
2569.14
11.02
+8
-4.08
-1.421
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
42 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 42 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of a novel tryptophan-rich membrane-active antimicrobial peptide from the membrane-proximal region of the HIV glycoprotein, gp41. | Beilstein J Org Chem | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis