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Peptide record

TPDB09112

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09112
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLRKWGKKWKEFLRRVWK
Physicochemical Analysis
C122H192N36O22
ANDCQHIMPSTY
K
2515.09
12.17
8
1
8
+7
1.13
-1.137
76.84
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
656.04
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
0
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
19
C122H192N36O22
2515.09
12.17
+7
1.13
-1.137
Evidence Records 2 records
Evidence 1 Activity

Activity

34.46% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
34.46% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Lipid selectivity in novel antimicrobial peptides: Implication on antimicrobial and hemolytic activity. | Colloids Surf B Biointerfaces | 2017
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
34.46 %
Hemolytic
Hemolytic_activity: [Ref.28236791] 34.46% hemolysis at 128 µg/ml

Target

erythrocytes

Source & Reference

NA
DRAMP
Colloids Surf B Biointerfaces. 2017 May 1 153:152-159. doi: 10.1016/j.colsurfb.2017.02.003.