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Peptide record

TPDB09111

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09111
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLLKKWLKKWKEFKRIVGY
Physicochemical Analysis
C120H190N30O23
ANDCQHMPST
K
2421.02
10.86
7
1
9
+6
1.10
-0.653
97.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
515.90
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
1
I
3
L
6
K
0
M
1
F
0
P
0
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
19
C120H190N30O23
2421.02
10.86
+6
1.10
-0.653
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
160 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 160 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates. | Eur J Med Chem | 2014