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Peptide record

TPDB09109

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09109
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GKPYGNAYLGLRPKYSRWL
Physicochemical Analysis
C106H159N29O25
DCEQHIMFTV
GLY
2239.61
10.47
4
0
8
+4
-1.44
-0.900
66.84
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
9970
445.17
5
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
3
L
2
K
0
M
0
F
2
P
1
S
0
T
1
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 3 K: 2 M: 0 F: 0 P: 2 S: 1 T: 0 W: 1 Y: 3 V: 0
Chemical Descriptors
19
C106H159N29O25
2239.61
10.47
+4
-1.44
-0.900
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
5% Hemolysis | >256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The influence of isoleucine and arginine on biological activity and peptide-membrane interactions of antimicrobial peptides from the bactericidal domain of AvBD4. | Protein Pept Lett | 2013