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Peptide record

TPDB09090

Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09090
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KILRGVSKKIMRRILTGKK
Physicochemical Analysis
C99H189N33O22S1
ANDCEQHFPWY
K
2225.86
12.72
8
0
7
+8
5.46
-0.426
117.89
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
2
L
5
K
1
M
0
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 2 K: 5 M: 1 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C99H189N33O22S1
2225.86
12.72
+8
5.46
-0.426
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens. | J Biol Chem | 2007
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: <5% Hemolysis=100 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2007 May 18 282(20):14719-28.