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Peptide record

TPDB09084

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09084
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RRWQWRLCYCRRRFCVCVG
Physicochemical Analysis
C111H172N40O22S4
ANDEHIKMPST
R
2547.08
10.92
6
0
7
+6
-1.70
-0.474
51.05
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12740
500.18
6
Residue Composition
number
0
A
6
R
0
N
0
D
4
C
0
E
1
Q
1
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 4 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 2
Chemical Descriptors
19
C111H172N40O22S4
2547.08
10.92
+6
-1.70
-0.474
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 256 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Design of hybrid ?-hairpin peptides with enhanced cell specificity and potent anti-inflammatory activity | Biomaterials | 2013