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Peptide record

TPDB09083

Antibacterial Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09083
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RPPQFTRAQWFAIQHISLN
Physicochemical Analysis
C107H160N32O26
DCEGKMYV
Q
2310.65
12.40
3
0
8
+2
0.28
-0.516
72.11
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
238.03
6
Residue Composition
number
2
A
2
R
1
N
0
D
0
C
0
E
3
Q
0
G
1
H
2
I
1
L
0
K
0
M
2
F
2
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 3 G: 0 H: 1 I: 2 L: 1 K: 0 M: 0 F: 2 P: 2 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
19
C107H160N32O26
2310.65
12.40
+2
0.28
-0.516
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
11.2±0.1 µM
Hemolytic Cytotoxic
50% Hemolysis | 11.2±0.1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Refining the eosinophil cationic protein antibacterial pharmacophore by rational structure minimization. | J Med Chem | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis