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Peptide record

TPDB09082

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09082
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QPEWFKARRWQWRMKKLGA
Physicochemical Analysis
C117H176N36O24S1
NDCHISTYV
RKW
2502.97
12.14
6
1
8
+5
1.23
-1.489
31.05
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
16500
659.22
2
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
1
E
2
Q
1
G
0
H
0
I
1
L
3
K
1
M
1
F
1
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 0 L: 1 K: 3 M: 1 F: 1 P: 1 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
19
C117H176N36O24S1
2502.97
12.14
+5
1.23
-1.489
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
2% Hemolysis | 400 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Designed low amphipathic peptides with alpha-helical propensity exhibiting antimicrobial activity via a lipid domain formation mechanism. | Peptides | 2010