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Peptide record

TPDB09069

Antibacterial Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB09069
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FFSMIPHIATGIASLVKNL
Physicochemical Analysis
C97H155N23O24S1
RDCEQWY
I
2059.50
10.10
2
0
11
+1
-1.58
1.132
128.42
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
3
I
2
L
1
K
1
M
2
F
1
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 3 L: 2 K: 1 M: 1 F: 2 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C97H155N23O24S1
2059.50
10.10
+1
-1.58
1.132
Evidence Records 5 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 16 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 32 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 3 Activity

Activity

20% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 4 Activity

Activity

100% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis. | Toxins (Basel) | 2016
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis