Back to search

Peptide record

TPDB09049

Antibacterial Antifungal Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB09049
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 19-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GSLHGFMYRYLKNMVLNLF
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C108H163N27O25S2
ADCEQIPTW
L
2303.77
10.08
3
0
11
+2
0.31
0.316
97.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
1.29
5
Residue Composition
number
0
A
1
R
2
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
4
L
1
K
2
M
2
F
0
P
1
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 4 K: 1 M: 2 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
19 reviewed residue count
C108H163N27O25S2 sequence-only estimate (linear, free termini)
2303.77 sequence-only estimate (linear, free termini)
10.08 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
0.31 sequence-only estimate (linear, free termini)
0.316 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
1-32 µM
Hemolytic Cytotoxic
0% Hemolysis | 1-32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 2 Activity

Activity

2.18±1.62% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
2.18±1.62% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017
Evidence 3 Activity

Activity

8.01±2.16% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
8.01±2.16% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Encrypted Antimicrobial Peptides from Plant Proteins. | Sci Rep | 2017