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Peptide record

TPDB09021

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB09021
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ITKQITKQLNRQTKIQSK
Physicochemical Analysis
C93H170N30O28
ADCEGHMFPWYV
QK
2156.56
11.80
5
0
4
+5
6.57
-1.289
86.67
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
9
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
4
Q
0
G
0
H
3
I
1
L
4
K
0
M
0
F
0
P
1
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 4 G: 0 H: 0 I: 3 L: 1 K: 4 M: 0 F: 0 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C93H170N30O28
2156.56
11.80
+5
6.57
-1.289
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>250 µM
Hemolytic Cytotoxic
50% Hemolysis | >250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Helminth Defense Molecules as Design Templates for Membrane Active Antibiotics. | ACS Infect Dis | 2019