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Peptide record

TPDB09011

Antibacterial Anticancer Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB09011
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ICRKPIICRKPIICRKPI
Physicochemical Analysis
C96H176N30O19S3
ANDEQGHLMFSTWYV
I
2150.82
10.81
6
0
6
+6
4.17
0.250
130.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
125
5.81
3
Residue Composition
number
0
A
3
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
6
I
0
L
3
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 6 L: 0 K: 3 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C96H176N30O19S3
2150.82
10.81
+6
4.17
0.250
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational Avoidance of Protease Cleavage Sites and Symmetrical End-Tagging Significantly Enhances the Stability and Therapeutic Potential of Antimicrobial Peptides | J Med Chem | 2020
Evidence 2 Activity

Activity

10% Killing
Toxicity
128 µM
Cytotoxic
10% Killing | 128 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Rational Avoidance of Protease Cleavage Sites and Symmetrical End-Tagging Significantly Enhances the Stability and Therapeutic Potential of Antimicrobial Peptides | J Med Chem | 2020