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Peptide record

TPDB08979

Antibacterial Anticancer Antifungal Antiparasitic standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08979
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia Antifungipept
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GNNRPIYIPQPRPPHPRL
Physicochemical Analysis
C96H152N32O23
ADCEKMFSTWV
P
2122.46
12.11
4
0
4
+3
5.40
-1.428
65.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
70.20
4
Residue Composition
number
0
A
3
R
2
N
0
D
0
C
0
E
1
Q
1
G
1
H
2
I
1
L
0
K
0
M
0
F
6
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 2 L: 1 K: 0 M: 0 F: 0 P: 6 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18
C96H152N32O23
2122.46
12.11
+3
5.40
-1.428
Evidence Records 39 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.2 µg/mL

Target

A. tumefaciens DSM 3129

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae p
Evidence 2 Activity

Activity

MIC
Antibacterial
0.02 µg/mL

Target

E. salicis NCPPB 2530

Source & Reference

dbAMP DRAMP

Other

active against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R
Evidence 3 Activity

Activity

MIC
Antibacterial
0.1 µg/mL

Target

Escherichia coli NCTC 9001

Source & Reference

dbAMP DRAMP

Other

against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml),
Evidence 4 Activity

Activity

MIC
Antibacterial
0.1 µg/mL

Target

v. tomamta NCPPB 1105

Source & Reference

dbAMP DRAMP

Other

, E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium AT
Evidence 5 Activity

Activity

MIC
Antibacterial
0.02 µg/mL

Target

R. meliloti ZB 314

Source & Reference

dbAMP DRAMP

Other

), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescen
Evidence 6 Activity

Activity

MIC
Antibacterial
0.2 µg/mL

Target

S. Newport CD 94

Source & Reference

dbAMP DRAMP

Other

P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S.
Evidence 7 Activity

Activity

MIC
Antibacterial
0.1 µg/mL

Target

S. typhimurium ATCC 23565

Source & Reference

dbAMP DRAMP

Other

5 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidios
Evidence 8 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

S.marcescens ATCC 17991

Source & Reference

dbAMP DRAMP

Other

0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG
Evidence 9 Activity

Activity

MIC
Antibacterial
0.1 µg/mL

Target

S. flexneri CP 87

Source & Reference

dbAMP DRAMP

Other

ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megater
Evidence 10 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

C. insidiosum NCPPB 1109

Source & Reference

dbAMP DRAMP

Other

0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis N
Evidence 11 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

B. megaterium OMB 1551

Source & Reference

dbAMP DRAMP

Other

0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >2
Evidence 12 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

B.subtilis NRRL-B-237

Source & Reference

dbAMP DRAMP

Other

C 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >200 ug/ml). Updated 7/2014 7/2021 9/20
Evidence 13 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

B.thuringiensis tenebrionis DSM 2803

Source & Reference

dbAMP DRAMP

Other

/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >200 ug/ml). Updated 7/2014 7/2021 9/2023.
Evidence 14 Activity

Activity

MIC
Antifungal
0.2 µg/mL

Target

A. tumefaciens DSM 3129

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae p
Evidence 15 Activity

Activity

MIC
Antifungal
0.02 µg/mL

Target

E. salicis NCPPB 2530

Source & Reference

dbAMP DRAMP Antifungipept

Other

active against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R
Evidence 16 Activity

Activity

MIC
Antifungal
0.1 µg/mL

Target

Escherichia coli NCTC 9001

Source & Reference

dbAMP DRAMP Antifungipept

Other

against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml),
Evidence 17 Activity

Activity

MIC
Antifungal
0.1 µg/mL

Target

v. tomamta NCPPB 1105

Source & Reference

dbAMP DRAMP Antifungipept

Other

, E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium AT
Evidence 18 Activity

Activity

MIC
Antifungal
0.02 µg/mL

Target

R. meliloti ZB 314

Source & Reference

dbAMP DRAMP Antifungipept

Other

), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescen
Evidence 19 Activity

Activity

MIC
Antifungal
0.2 µg/mL

Target

S. Newport CD 94

Source & Reference

dbAMP DRAMP Antifungipept

Other

P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S.
Evidence 20 Activity

Activity

MIC
Antifungal
0.1 µg/mL

Target

S. typhimurium ATCC 23565

Source & Reference

dbAMP DRAMP Antifungipept

Other

5 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidios
Evidence 21 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

S.marcescens ATCC 17991

Source & Reference

dbAMP DRAMP Antifungipept

Other

0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG
Evidence 22 Activity

Activity

MIC
Antifungal
0.1 µg/mL

Target

S. flexneri CP 87

Source & Reference

dbAMP DRAMP Antifungipept

Other

ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megater
Evidence 23 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

C. insidiosum NCPPB 1109

Source & Reference

dbAMP DRAMP Antifungipept

Other

0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis N
Evidence 24 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

B. megaterium OMB 1551

Source & Reference

dbAMP DRAMP Antifungipept

Other

0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >2
Evidence 25 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

B.subtilis NRRL-B-237

Source & Reference

dbAMP DRAMP Antifungipept

Other

C 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >200 ug/ml). Updated 7/2014 7/2021 9/20
Evidence 26 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

B.thuringiensis tenebrionis DSM 2803

Source & Reference

dbAMP DRAMP Antifungipept

Other

/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >200 ug/ml). Updated 7/2014 7/2021 9/2023.
Evidence 27 Activity

Activity

MIC
Antiparasitic
0.2 µg/mL

Target

A. tumefaciens DSM 3129

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae p
Evidence 28 Activity

Activity

MIC
Antiparasitic
0.02 µg/mL

Target

E. salicis NCPPB 2530

Source & Reference

DRAMP

Other

active against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R
Evidence 29 Activity

Activity

MIC
Antiparasitic
0.1 µg/mL

Target

Escherichia coli NCTC 9001

Source & Reference

DRAMP

Other

against A. tumefaciens DSM 3129 (MIC 0.2 ug/ml), E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml),
Evidence 30 Activity

Activity

MIC
Antiparasitic
0.1 µg/mL

Target

v. tomamta NCPPB 1105

Source & Reference

DRAMP

Other

, E. salicis NCPPB 2530 (MIC 0.02 ug/ml), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium AT
Evidence 31 Activity

Activity

MIC
Antiparasitic
0.02 µg/mL

Target

R. meliloti ZB 314

Source & Reference

DRAMP

Other

), E. coli NCTC 9001 (MIC 0.1 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescen
Evidence 32 Activity

Activity

MIC
Antiparasitic
0.2 µg/mL

Target

S. Newport CD 94

Source & Reference

DRAMP

Other

P. syringae pv. tomamta NCPPB 1105 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S.
Evidence 33 Activity

Activity

MIC
Antiparasitic
0.1 µg/mL

Target

S. typhimurium ATCC 23565

Source & Reference

DRAMP

Other

5 (MIC 0.1 ug/ml), R. meliloti ZB 314 (MIC 0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidios
Evidence 34 Activity

Activity

MIC
Antiparasitic
>200 µg/mL

Target

S.marcescens ATCC 17991

Source & Reference

DRAMP

Other

0.02 ug/ml), S. Newport CD 94 (MIC 0.2 ug/ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG
Evidence 35 Activity

Activity

MIC
Antiparasitic
0.1 µg/mL

Target

S. flexneri CP 87

Source & Reference

DRAMP

Other

ml), S. typhimurium ATCC 23565 (MIC 0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megater
Evidence 36 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

C. insidiosum NCPPB 1109

Source & Reference

DRAMP

Other

0.1 ug/ml), S.marcescens ATCC 17991 (MIC >200 ug/ml), S. flexneri CP 87 (MIC 0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis N
Evidence 37 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

B. megaterium OMB 1551

Source & Reference

DRAMP

Other

0.1 ug/ml), C. insidiosum NCPPB 1109 (MIC 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >2
Evidence 38 Activity

Activity

MIC
Antiparasitic
>200 µg/mL

Target

B.subtilis NRRL-B-237

Source & Reference

DRAMP

Other

C 100 ug/ml), B.alvei LMG 6922 (MIC > 200 ug/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >200 ug/ml). Updated 7/2014 7/2021 9/20
Evidence 39 Activity

Activity

MIC
Antiparasitic
>200 µg/mL

Target

B.thuringiensis tenebrionis DSM 2803

Source & Reference

DRAMP

Other

/ml), B. megaterium OMB 1551 (MIC 100 ug/ml), B.subtilis NRRL-B-237 (MIC >200 ug/ml), and B.thuringiensis tenebrionis DSM 2803 (MIC >200 ug/ml). Updated 7/2014 7/2021 9/2023.