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Peptide record

TPDB08970

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08970
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 i2APP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ALYKKFKKKLLKSLKRLG
Physicochemical Analysis
C104H184N28O21
NDCEQHIMPTWV
K
2162.78
11.28
8
0
8
+8
2.84
-0.594
113.89
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
68.89
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
5
L
7
K
0
M
1
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 5 K: 7 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18
C104H184N28O21
2162.78
11.28
+8
2.84
-0.594
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>100 µM
Cytotoxic
50% Cytotoxicity | >100 | µM | target cell: Murine peritoneal macrophages

Target

Murine peritoneal macrophages

Source & Reference

NA
DBAASP
Antimicrobial Activity of RP-1 Peptide Conjugate With Ferrocene Group. | PLoS One | 2020
Evidence 2 Activity

Activity

7% Hemolysis
Toxicity
4.3 µM
Hemolytic Cytotoxic
7% Hemolysis | 4.3 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of RP-1 Peptide Conjugate With Ferrocene Group. | PLoS One | 2020
Evidence 3 Activity

Activity

53% Hemolysis
Toxicity
66.29 µM
Hemolytic Cytotoxic
53% Hemolysis | 66.29 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of RP-1 Peptide Conjugate With Ferrocene Group. | PLoS One | 2020
Evidence 4 Activity

Activity

0% Cytotoxicity
Toxicity
220 µM
Cytotoxic
0% Cytotoxicity | 220 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Antimicrobial Activity of RP-1 Peptide Conjugate With Ferrocene Group. | PLoS One | 2020