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Peptide record

TPDB08964

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08964
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
HNSSKQWSHWLWHNGIRI
Physicochemical Analysis
C105H148N34O25
ADCEMFPTYV
HSW
2286.54
11.49
5
0
6
+2
-0.23
-1.178
65.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
16500
721.61
6
Residue Composition
number
0
A
1
R
2
N
0
D
0
C
0
E
1
Q
1
G
3
H
2
I
1
L
1
K
0
M
0
F
0
P
3
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 3 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 3 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
18
C105H148N34O25
2286.54
11.49
+2
-0.23
-1.178
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans ATCC 14053 (MIC 64 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here. Updated 7
Evidence 2 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. albicans ATCC 14053 (MIC 64 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here. Updated 7
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016