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Peptide record

TPDB08956

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08956
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NILSSIVNGINRALSFFG
Physicochemical Analysis
C87H140N24O25
DCEQHKMPTWY
NIS
1922.21
11.05
1
0
9
+1
-1.93
0.806
130.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
6
Residue Composition
number
1
A
1
R
3
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
2
L
0
K
0
M
2
F
0
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 2 K: 0 M: 0 F: 2 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C87H140N24O25
1922.21
11.05
+1
-1.93
0.806
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Gram bacteria S. aureus ATCC2592 (MIC 37.5 ug/ml), B. pumilus (MIC 75 ug/ml), B.cereus (ND), Gram- bacteria E.coli ATCC25922 (ND), B.dysent
Evidence 2 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

B. pumilus

Source & Reference

dbAMP

Other

Gram bacteria S. aureus ATCC2592 (MIC 37.5 ug/ml), B. pumilus (MIC 75 ug/ml), B.cereus (ND), Gram- bacteria E.coli ATCC25922 (ND), B.dysenteriae (ND), A.calcoaceticus
Evidence 3 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Gram bacteria S. aureus ATCC2592 (MIC 37.5 ug/ml), B. pumilus (MIC 75 ug/ml), B.cereus (ND), Gram- bacteria E.coli ATCC25922 (ND), B.dysent
Evidence 4 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

B. pumilus

Source & Reference

dbAMP CAFPdb

Other

Gram bacteria S. aureus ATCC2592 (MIC 37.5 ug/ml), B. pumilus (MIC 75 ug/ml), B.cereus (ND), Gram- bacteria E.coli ATCC25922 (ND), B.dysenteriae (ND), A.calcoaceticus
Evidence 5 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

NA

Other

Gram bacteria S. aureus ATCC2592 (MIC 37.5 ug/ml), B. pumilus (MIC 75 ug/ml), B.cereus (ND), Gram- bacteria E.coli ATCC25922 (ND), B.dysent
Evidence 6 Activity

Activity

MIC
Antiparasitic
75 µg/mL

Target

B. pumilus

Source & Reference

NA

Other

Gram bacteria S. aureus ATCC2592 (MIC 37.5 ug/ml), B. pumilus (MIC 75 ug/ml), B.cereus (ND), Gram- bacteria E.coli ATCC25922 (ND), B.dysenteriae (ND), A.calcoaceticus
Evidence 7 Activity

Activity

3% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 200 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
A novel family of antimicrobial peptides from the skin of Amolops loloensis | Biochimie | 2008