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Peptide record

TPDB08952

Antibacterial Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08952
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GVLSAFKNALPGIMKIIV
Physicochemical Analysis
C88H151N21O21S1
RDCEQHTWY
I
1871.35
10.60
2
0
11
+2
-0.61
1.294
151.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
2
L
2
K
1
M
1
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 2 K: 2 M: 1 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C88H151N21O21S1
1871.35
10.60
+2
-0.61
1.294
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
34 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 34 uM), S. aureus (MIC 4.3 uM), and C. albicans (MIC 4-9 uM). Reg. 8/2014.
Evidence 2 Activity

Activity

MIC
Antibacterial
4.3 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 34 uM), S. aureus (MIC 4.3 uM), and C. albicans (MIC 4-9 uM). Reg. 8/2014.
Evidence 3 Activity

Activity

MIC
Antibacterial
4-9 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Active against E. coli (MIC 34 uM), S. aureus (MIC 4.3 uM), and C. albicans (MIC 4-9 uM). Reg. 8/2014.
Evidence 4 Activity

Activity

MIC
Antifungal
34 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 34 uM), S. aureus (MIC 4.3 uM), and C. albicans (MIC 4-9 uM). Reg. 8/2014.
Evidence 5 Activity

Activity

MIC
Antifungal
4.3 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 34 uM), S. aureus (MIC 4.3 uM), and C. albicans (MIC 4-9 uM). Reg. 8/2014.
Evidence 6 Activity

Activity

MIC
Antifungal
4-9 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 34 uM), S. aureus (MIC 4.3 uM), and C. albicans (MIC 4-9 uM). Reg. 8/2014.
Evidence 7 Activity

Activity

3% Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 8 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Hylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii. | Amino Acids | 2014
Evidence 8 Activity

Activity

4% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 16 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Hylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii. | Amino Acids | 2014
Evidence 9 Activity

Activity

23% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
23% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Hylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii. | Amino Acids | 2014
Evidence 10 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.