Back to search

Peptide record

TPDB08950

Antibacterial Anticancer Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08950
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia SATPdb Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, SATPdb, and other sources, with an available 3D structural model.
Sequence
GEKLKKIGQKIKNFFQKL
Physicochemical Analysis
C101H171N27O24
ARDCHMPSTWYV
K
2147.64
10.82
6
1
6
+5
5.56
-0.889
86.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
1
E
2
Q
2
G
0
H
2
I
2
L
6
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 2 G: 2 H: 0 I: 2 L: 2 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C101H171N27O24
2147.64
10.82
+5
5.56
-0.889
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli KCTC 1682

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
CRAMP18 is active against E. coli KCTC 1682 (MIC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtil
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

S. typhimurium KCTC 1926

Source & Reference

dbAMP

Other

CRAMP18 is active against E. coli KCTC 1682 (MIC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KC
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Pseudomonas aeruginosa KCTC 1637

Source & Reference

dbAMP

Other

is active against E. coli KCTC 1682 (MIC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µM

Target

B. subtilis KCTC 1918

Source & Reference

dbAMP

Other

IC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50
Evidence 5 Activity

Activity

MIC
Antibacterial
50 µM

Target

Streptococcus pyogenes KCTC 3096

Source & Reference

dbAMP

Other

(MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50 uM), A. fumigatus (MIC 100 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
50 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

CTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50 uM), A. fumigatus (MIC 100 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
100 µM

Target

A. fumigatus

Source & Reference

dbAMP

Other

pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50 uM), A. fumigatus (MIC 100 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
50 µM

Target

Escherichia coli KCTC 1682

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
CRAMP18 is active against E. coli KCTC 1682 (MIC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtil
Evidence 9 Activity

Activity

MIC
Antifungal
12.5 µM

Target

S. typhimurium KCTC 1926

Source & Reference

dbAMP CAFPdb Antifungipept

Other

CRAMP18 is active against E. coli KCTC 1682 (MIC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KC
Evidence 10 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Pseudomonas aeruginosa KCTC 1637

Source & Reference

dbAMP CAFPdb Antifungipept

Other

is active against E. coli KCTC 1682 (MIC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621
Evidence 11 Activity

Activity

MIC
Antifungal
50 µM

Target

B. subtilis KCTC 1918

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 50 uM), S. typhimurium KCTC 1926 (MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50
Evidence 12 Activity

Activity

MIC
Antifungal
50 µM

Target

Streptococcus pyogenes KCTC 3096

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 12.5 uM), P. aeruginosa KCTC 1637 (MIC 12.5 uM), B. subtilis KCTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50 uM), A. fumigatus (MIC 100 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
50 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

CTC 1918 (MIC 50 uM), S. pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50 uM), A. fumigatus (MIC 100 uM).
Evidence 14 Activity

Activity

MIC
Antifungal
100 µM

Target

A. fumigatus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

pyogenes KCTC 3096 (MIC 50 uM), S-aureus KCTC 1621 (MIC >50 uM), C. albicans (MIC 50 uM), A. fumigatus (MIC 100 uM).
Evidence 15 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity | Biochem Biophys Res Commun | 2000