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Peptide record

TPDB08946

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08946
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRWCFRVCYKGFCRYKCR
Physicochemical Analysis
C108H164N36O21S4
ANDEQHILMPST
R
2430.96
10.36
7
0
6
+7
-0.84
-0.800
16.11
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8730
359.12
6
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
2
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
18
C108H164N36O21S4
2430.96
10.36
+7
-0.84
-0.800
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
85 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 85 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers. | Biochemistry | 2000
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis