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Peptide record

TPDB08943

Antibacterial Antifungal Antiparasitic Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08943
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb dbAMP 3.0 ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LLGMIPVAISAISALSKL
Physicochemical Analysis
C83H149N19O22S1
RNDCEQHFTWY
L
1797.27
10.10
1
0
12
+1
-2.00
1.772
184.44
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
4
L
1
K
1
M
0
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 4 K: 1 M: 1 F: 0 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C83H149N19O22S1
1797.27
10.10
+1
-2.00
1.772
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus (MIC 25-32 mg/L), E. faecalis ATCC 29212 (MIC 100 uM), and C.albicans (MIC 128 mg/L). Also discovered in Phyllomedusa sauvagii ( Raja et al., 2
Evidence 2 Activity

Activity

MIC
Antifungal
100 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus (MIC 25-32 mg/L), E. faecalis ATCC 29212 (MIC 100 uM), and C.albicans (MIC 128 mg/L). Also discovered in Phyllomedusa sauvagii ( Raja et al., 2
Evidence 3 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against S. aureus (MIC 25-32 mg/L), E. faecalis ATCC 29212 (MIC 100 uM), and C.albicans (MIC 128 mg/L). Also discovered in Phyllomedusa sauvagii ( Raja et al., 2
Evidence 4 Activity

Activity

2% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Medusins: a new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs. | Biochimie | 2013