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Peptide record

TPDB08942

Antibacterial Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08942
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LLGMIPLAISAISSLSKL
Physicochemical Analysis
C84H151N19O23S1
RNDCEQHFTWYV
L
1827.30
10.10
1
0
11
+1
-2.33
1.606
184.44
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
5
L
1
K
1
M
0
F
1
P
4
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 5 K: 1 M: 1 F: 0 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C84H151N19O23S1
1827.30
10.10
+1
-2.33
1.606
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against S. aureus (MIC 32 mg/L) and C. albicans (MIC 64 mg/L).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against S. aureus (MIC 32 mg/L) and C. albicans (MIC 64 mg/L).
Evidence 3 Activity

Activity

7% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Medusins: a new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs. | Biochimie | 2013
Evidence 4 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.