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Peptide record

TPDB08941

Antibacterial Anticancer Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08941
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP dbAMP 3.0 iACP-DRLF pep-lab HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KWKLFKKISKFLHLAKKF
Physicochemical Analysis
C116H184N28O20
RNDCEQGMPTYV
K
2290.91
11.29
8
0
9
+7
0.62
-0.339
92.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
240.08
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
7
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 7 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C116H184N28O20
2290.91
11.29
+7
0.62
-0.339
Evidence Records 8 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
3.125 µM
Hemolytic Cytotoxic
0% Hemolysis | 3.125 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 2 Activity

Activity

2% Hemolysis
Toxicity
6.25 µM
Hemolytic Cytotoxic
2% Hemolysis | 6.25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
5% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 4 Activity

Activity

11% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
11% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 5 Activity

Activity

22% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
22% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 7 Activity

Activity

IC50
Toxicity
50.0 µM
Cytotoxic
IC50 | 50.0 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs. | J Pept Res | 2001
Evidence 8 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis