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Peptide record

TPDB08937

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08937
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifp
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KWKLFKKIGIGAVLKVLT
Physicochemical Analysis
C101H172N24O20
RNDCEQHMPSY
K
2042.63
11.12
5
0
10
+5
-0.20
0.639
146.11
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
269.26
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
5
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
18
C101H172N24O20
2042.63
11.12
+5
-0.20
0.639
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Antibacterial
4 µM

Target

P. falciparum

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
0.5 uM), S. aureus Cowan 1 (LC 7 uM), and S. pyogenes (LC 0.8 uM). Antimalarial activity:P. falciparum (IC50 4 uM).
Evidence 2 Activity

Activity

IC50
Antifungal
4 µM

Target

P. falciparum

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
0.5 uM), S. aureus Cowan 1 (LC 7 uM), and S. pyogenes (LC 0.8 uM). Antimalarial activity:P. falciparum (IC50 4 uM).
Evidence 3 Activity

Activity

IC50
Antiparasitic
4 µM

Target

P. falciparum

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
0.5 uM), S. aureus Cowan 1 (LC 7 uM), and S. pyogenes (LC 0.8 uM). Antimalarial activity:P. falciparum (IC50 4 uM).