Peptide record

TPDB08916

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08916
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LKDVEEAQQKIINIIRRL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C96H171N29O28
CGHMFPSTWY
I
2179.59
9.88
4
3
8
+1
2.53
-0.344
151.67
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
2
R
1
N
1
D
0
C
2
E
2
Q
0
G
0
H
4
I
2
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 1 C: 0 E: 2 Q: 2 G: 0 H: 0 I: 4 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18 reviewed residue count
C96H171N29O28 sequence-only estimate (linear, free termini)
2179.59 sequence-only estimate (linear, free termini)
9.88 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
2.53 sequence-only estimate (linear, free termini)
-0.344 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha-helices in proteins: results from analysis of protein structures. | Proteins | 2005