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Peptide record

TPDB08914

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08914
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
KQLIRFLKRLDRNLWGLA
Physicochemical Analysis
C104H174N32O23
CEHMPSTYV
L
2240.73
12.13
5
1
9
+4
0.39
-0.278
135.56
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
245.46
2
Residue Composition
number
1
A
3
R
1
N
1
D
0
C
0
E
1
Q
1
G
0
H
1
I
5
L
2
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 5 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C104H174N32O23
2240.73
12.13
+4
0.39
-0.278
Evidence Records 2 records
Evidence 1 Activity

Activity

48% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
48% Hemolysis | 10 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha-helices in proteins: results from analysis of protein structures. | Proteins | 2005
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis