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Peptide record

TPDB08912

C5 Antibacterial Cell-penetrating Peptides Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08912
C5
Antibacterial Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0 PerseuCPP HemoPI Hemolytic2
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
KLLKLLLKLWKKLLKLLK
Physicochemical Analysis
C113H206N26O19
ARNDCEQGHIMFPSTYV
L
2233.04
11.29
7
0
11
+7
-0.52
0.544
216.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
246.30
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
10
L
7
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 10 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C113H206N26O19
2233.04
11.29
+7
-0.52
0.544
Free
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

C166-eGFP cells

Source & Reference

CPPsite3.0
CPPsite3
WO 2011/020188 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCHHHHTTTTHHHHHHHC
Evidence 2 Hemolysis

Source & Reference

HemoPI
NA
Additional Detail Fields 1 fields
CCHHHHTTTTHHHHHHHC