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Peptide record

TPDB08905

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08905
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GMASLLAKVLPHVVKLIK
Physicochemical Analysis
C90H161N23O20S1
RNDCEQFTWY
L
1917.47
10.84
4
0
11
+3
1.61
1.117
167.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
4
L
3
K
1
M
0
F
1
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 4 K: 3 M: 1 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
18
C90H161N23O20S1
1917.47
10.84
+3
1.61
1.117
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
B. subtilis (2.5 uM), S. aureus (3.7 uM), E. coli (3.7 uM), P. aeruginosa (31.7 uM), and C. albicans (MIC 25 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
25 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
B. subtilis (2.5 uM), S. aureus (3.7 uM), E. coli (3.7 uM), P. aeruginosa (31.7 uM), and C. albicans (MIC 25 uM).
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
105 µM
Hemolytic Cytotoxic
50% Hemolysis | 105 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Interaction of a novel antimicrobial peptide isolated from the venom of solitary bee Colletes daviesanus with phospholipid vesicles and Escherichia coli cells. | J Pept Sci | 2014