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Peptide record

TPDB08895

Antibacterial Anticancer Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08895
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia SATPdb Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, SATPdb, and other sources, with an available 3D structural model.
Sequence
GEKLKKIGQKIKKFFQKL
Physicochemical Analysis
C103H177N27O23
ARNDCHMPSTWYV
K
2161.71
10.92
7
1
6
+6
6.13
-0.911
86.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
2
Q
2
G
0
H
2
I
2
L
7
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 2 G: 2 H: 0 I: 2 L: 2 K: 7 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C103H177N27O23
2161.71
10.92
+6
6.13
-0.911
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity | Biochem Biophys Res Commun | 2000
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: Not active up to 100 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochem Biophys Res Commun. 2000 Sep 7 275(3):904-9.