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Peptide record

TPDB08893

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08893
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Hemolytic2 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
FRKLFRVYSNFLRGKLKL
Physicochemical Analysis
C110H177N31O22
ADCEQHIMPTW
L
2285.81
12.15
6
0
9
+6
-0.54
-0.189
102.78
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
65.18
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
4
L
3
K
0
M
3
F
0
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 3 M: 0 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C110H177N31O22
2285.81
12.15
+6
-0.54
-0.189
Evidence Records 2 records
Evidence 1 Activity

Activity

62% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
62% Hemolysis | 10 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Amphipathic alpha-helices in proteins: results from analysis of protein structures. | Proteins | 2005
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis