Back to search

Peptide record

TPDB08889

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB08889
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
FDWDSVLKGVEGFVRGYF
Physicochemical Analysis
C102H141N23O27
ANCQHIMPT
GFV
2121.38
4.31
2
3
9
-1
-0.09
0.094
70.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
329.50
2
Residue Composition
number
0
A
1
R
0
N
2
D
0
C
1
E
0
Q
3
G
0
H
0
I
1
L
1
K
0
M
3
F
0
P
1
S
0
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 1 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 3
Chemical Descriptors
18
C102H141N23O27
2121.38
4.31
-1
-0.09
0.094
Evidence Records 4 records
Evidence 1 Activity

Activity

15.2 ± 0.11% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
15.2 ± 0.11% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Strategic modification of low-activity natural antimicrobial peptides confers antibacterial potential in vitro and in vivo. | Eur J Med Chem | 2023
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Tilapia erythrocytes

Target

Tilapia erythrocytes

Source & Reference

NA
DBAASP
Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. | PLoS One | 2012
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. | PLoS One | 2012
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Tilapia ovary TO2 cells

Target

Tilapia ovary TO2 cells

Source & Reference

NA
DBAASP
Five different piscidins from Nile tilapia, Oreochromis niloticus: analysis of their expressions and biological functions. | PLoS One | 2012