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Peptide record

TPDB08885

Antibacterial Cell-penetrating Peptides Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08885
Antibacterial Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CellPPD, and other sources, with an available 3D structural model.
Sequence
KALKKLLAKWLAAAKALL
Physicochemical Analysis
C95H168N24O19
RNDCEQGHIMFPSTYV
AL
1950.53
11.12
5
0
13
+5
-1.28
0.733
163.33
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
281.97
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
5
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C95H168N24O19
1950.53
11.12
+5
-1.28
0.733
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
2.0 µM
Hemolytic Cytotoxic
50% Hemolysis | 2.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides | FEBS Lett | 1997
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis