TPDB08876

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.6-1.2 µM

Target

Target Organism A. viridans

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.2-2.5 µM

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. aci

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism B. megaterium

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 20-40 µM

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 20-40 µM

Target

Target Organism P. acidolactici

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. p

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.3-1.2 µM

Target

Target Organism Escherichia coli D22 or D31 or 1106

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.2-2.5 µM

Target

Target Organism S. typhimurium

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

0 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.2-2.5 µM

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM),

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.2-2.5 µM

Target

Target Organism Enterobacter cloacae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

r 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 u

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 20-40 µM

Target

Target Organism E. carotovora

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

yphimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 20-40 µM

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 u

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism N. crassa

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

oacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A.

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.2-2.5 µM

Target

Target Organism B. cinerea

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism N. haematococca

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pi

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism T. viride

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ngi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxys

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5-5 µM

Target

Target Organism A. brassicola

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

M), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 5-10 µM

Target

Target Organism F. culmorum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10-20 µM

Target

Target Organism A. pisi

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

0 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 20-40 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.6-1.2 µM

Target

Target Organism A. viridans

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.2-2.5 µM

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. aci

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism B. megaterium

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

active against Gram+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 20-40 µM

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

+ A. viridans (MIC 0.6-1.2 uM), M. luteus (MIC 1.2-2.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 20-40 µM

Target

Target Organism P. acidolactici

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

.5 uM), B. megaterium (MIC 2.5-5 uM), B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. p

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.3-1.2 µM

Target

Target Organism Escherichia coli D22 or D31 or 1106

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

B. subtilis (MIC 20-40 uM), S-aureus (MIC > 40 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.2-2.5 µM

Target

Target Organism S. typhimurium

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

0 uM), P. acidolactici (MIC 20-40 uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.2-2.5 µM

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

uM), Gram- E. coli D22 or D31 or 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM),

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.2-2.5 µM

Target

Target Organism Enterobacter cloacae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

r 1106 (MIC 0.3-1.2 uM), S. typhimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 u

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 20-40 µM

Target

Target Organism E. carotovora

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

yphimurium (MIC 1.2-2.5 uM), K. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 20-40 µM

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

. pneumoniae (MIC 1.2-2.5 uM), E. cloacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 u

Evidence 31 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism N. crassa

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

oacae (MIC 1.2-2.5 uM), E. carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A.

Evidence 32 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.2-2.5 µM

Target

Target Organism B. cinerea

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

carotovora (MIC 20-40 uM), P. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F

Evidence 33 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism N. haematococca

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

. aeruginosa (MIC 20-40 uM), fungi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pi

Evidence 34 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism T. viride

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

ngi N. crassa (MIC 2.5-5 uM), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxys

Evidence 35 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5-5 µM

Target

Target Organism A. brassicola

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

M), B. cinerea (MIC 1.2-2.5 uM), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 36 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 5-10 µM

Target

Target Organism F. culmorum

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

), N. haematococca (MIC 5-10 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 37 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10-20 µM

Target

Target Organism A. pisi

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

0 uM), T. viride (MIC 2.5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).

Evidence 38 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 20-40 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

5-5 uM), A. brassicola (MIC 2.5-5 uM), F. culmorum (MIC 5-10 uM), A. pisi (MIC 10-20 uM), F. oxysporum (MIC 20-40 uM).