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Peptide record

TPDB08849

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08849
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KAIAKSILKWIKSIAKAI
Physicochemical Analysis
C95H168N24O21
RNDCEQGHMFPTYV
IK
1982.53
11.12
5
0
11
+5
0.57
0.639
152.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
277.42
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
5
I
1
L
5
K
0
M
0
F
0
P
2
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 5 L: 1 K: 5 M: 0 F: 0 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C95H168N24O21
1982.53
11.12
+5
0.57
0.639
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1.8 µM
Hemolytic Cytotoxic
50% Hemolysis | 1.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides | FEBS Lett | 1997
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis