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Peptide record

TPDB08844

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08844
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
IAGERRYGTIYQGRLWAF
Physicochemical Analysis
C100H149N29O25
NDCHKMPSV
RG
2157.46
10.24
3
1
9
+2
-1.18
-0.372
76.11
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
8480
393.05
4
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
1
E
1
Q
3
G
0
H
2
I
1
L
0
K
0
M
1
F
0
P
0
S
1
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 2 V: 0
Chemical Descriptors
18
C100H149N29O25
2157.46
10.24
+2
-1.18
-0.372
Evidence Records 3 records
Evidence 1 Activity

Activity

9% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
9% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial activity of human neutrophil defensin HNP-1 analogs without cysteines | Antimicrob Agents Chemother | 2005
Evidence 2 Activity

Activity

14% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
14% Hemolysis | 40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial activity of human neutrophil defensin HNP-1 analogs without cysteines | Antimicrob Agents Chemother | 2005
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis