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Peptide record

TPDB08818

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08818
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LNALKKVFQGIHEAIKLI
Physicochemical Analysis
C96H163N25O23
RDCMPSTWY
ILK
2035.50
10.32
4
1
10
+2
2.95
0.539
157.22
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
1
Q
1
G
1
H
3
I
3
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 1 I: 3 L: 3 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C96H163N25O23
2035.50
10.32
+2
2.95
0.539
Evidence Records 2 records
Evidence 1 Activity

Activity

12.30% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
12.30% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018
Evidence 2 Activity

Activity

13.8% Cytotoxicity
Toxicity
100 µM
Cytotoxic
13.8% Cytotoxicity | 100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018