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Peptide record

TPDB08803

Antibacterial Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08803
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
YKLLKWLLLKLKALLEKL
Physicochemical Analysis
C112H192N24O22
RNDCQGHIMFPSTV
L
2226.90
10.47
5
1
12
+4
-1.03
0.600
200.56
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
6990
313.89
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
9
L
5
K
0
M
0
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 9 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
18
C112H192N24O22
2226.90
10.47
+4
-1.03
0.600
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
6.3 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 6.3 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rapid identification of compounds with enhanced antimicrobial activity by using conformationally defined combinatorial libraries. | Biochem J | 1996
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis