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Peptide record

TPDB08798

Antibacterial Antifungal Antiviral Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08798
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP AI4AVP AVPpred-BWR dbAMP 3.0 DRAVP 2.0 ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
WRKWRKRWWWRKWRKRWW
Physicochemical Analysis
C148H202N48O19
ANDCEQGHILMFPSTYV
W
2957.54
13.10
10
0
8
+10
-5.98
-2.767
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
44000
1487.72
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
8
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 8 Y: 0 V: 0
Chemical Descriptors
18
C148H202N48O19
2957.54
13.10
+10
-5.98
-2.767
Evidence Records 1 records
Evidence 1 Activity

Activity

% Hemolysis
Toxicity
15 %
Hemolytic Cytotoxic
Hemolytic_activity: [Ref.17681018]15% hemolysis against human red blood cells at 35 µM. | Cytotoxicity: [Ref.17681018]No significant cytotoxicity against Vero cells up to 40 µM.

Target

erythrocytes

Source & Reference

NA
DRAMP
FEBS J. 2007 Sep 274(17):4511-25.