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Peptide record

TPDB08760

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08760
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
NGVQPKYKWWKWWKKWWW
Physicochemical Analysis
C137H174N32O22
ARDCEHILMFST
W
2621.09
10.77
5
0
9
+5
-7.41
-1.772
16.11
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
39990
1525.70
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
0
L
5
K
0
M
0
F
1
P
0
S
0
T
7
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 1 S: 0 T: 0 W: 7 Y: 1 V: 1
Chemical Descriptors
18
C137H174N32O22
2621.09
10.77
+5
-7.41
-1.772
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
23 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 23 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving the antibacterial activity and selectivity of an ultra short peptide by hydrophobic and hydrophilic amino acid stretches. | Bioorg Med Chem Lett | 2013