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Peptide record

TPDB08751

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08751
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
SKVGRHGRRFGHRAHRKL
Physicochemical Analysis
C92H155N41O20
NDCEQIMPTWY
R
2155.51
13.01
10
0
4
+7
7.28
-1.628
43.33
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
3
G
3
H
0
I
1
L
2
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 3 I: 0 L: 1 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C92H155N41O20
2155.51
13.01
+7
7.28
-1.628
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
50% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of anti-microbial peptides with enhanced activity and low cytotoxicity based on the structure of the arginine/histidine-rich peptide, chensinin-1. | J Appl Microbiol | 2012