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Peptide record

TPDB08746

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB08746
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
RIRFPWPWRWPWWPRFRG
Physicochemical Analysis
C131H172N38O19
ANDCEQHLKMSTYV
RW
2583.05
13.00
5
0
8
+5
-5.96
-1.317
21.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
27500
1064.63
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
2
F
4
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 2 P: 4 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
18
C131H172N38O19
2583.05
13.00
+5
-5.96
-1.317
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
50% Hemolysis | 150 | µM | target cell: Buffalo erythrocytes

Target

Buffalo erythrocytes

Source & Reference

NA
DBAASP
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins. | PLoS One | 2015
Evidence 2 Activity

Activity

32% Hemolysis
Toxicity
60 µM
Hemolytic Cytotoxic
32% Hemolysis | 60 | µM | target cell: Buffalo erythrocytes

Target

Buffalo erythrocytes

Source & Reference

NA
DBAASP
Diversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins. | PLoS One | 2015